I don't think this problem has anything to do with "Waking Nighmare" since I never had it until recently, after completing the whole game and DLCs and started a new game. I just started having this problem on a fresh new game. I was loading my mods a few at a time, made sure the game started with them loaded, once in a while I made a new save with them. Now it CTD when I try to save (any method). Going back to earliest "pure" game (no mods at all, not even DLCs) also CTD on save now. This is the second time I've gone through this! I started this new game because my previous new game started to have the same problem. I tried Ignacio's fix, but it didnt' work. How can I create a new save, when that's the very problem to begin with? It CTD when I save! Ppl speculate this is a game issue, not a PC issue, but does anyone actually know for sure? This is really upsetting especially since it's a new game, just out of Helgen, not yet gone to Riverwood. I have all official DLCs.
Also, renaming "tmp" saves to just "ess" consistently results in them being unusable. There's an endless loading screen (even though I have SSME which fixes that), and when I hit Ctrl Alt Del for Windows Startup it says Skyrim is "not responding" forcing me to shut down. Seems like ANY old character I load and try to save it always CTD.